American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Oct 2001
Randomized Controlled Trial Comparative Study Clinical TrialA comparison of various routes and dosages of misoprostol for cervical ripening and the induction of labor.
The purpose of this study was to compare the efficacy of different routes of misoprostol administration for cervical ripening and the induction of labor. ⋯ At the doses studied, induction of labor with vaginally administered misoprostol is more efficacious than either oral-plus-vaginal or oral-only route of administration.
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Am. J. Obstet. Gynecol. · Oct 2001
Randomized Controlled Trial Comparative Study Clinical TrialRectal misoprostol versus intravenous oxytocin for the prevention of postpartum hemorrhage after vaginal delivery.
To compare rectally administered misoprostol to intravenously administered oxytocin for the management of third-stage labor. ⋯ Rectal misoprostol (400 microg) was no more effective than intravenous oxytocin in preventing postpartum hemorrhage.
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Am. J. Obstet. Gynecol. · Oct 2001
Comparative StudyAre women who are Jehovah's Witnesses at risk of maternal death?
The purpose of this study was to determine the rates of obstetric hemorrhage and maternal mortality in women who are Jehovah's Witnesses and to evaluate a protocol that uses erythropoietin to optimize the red blood cell mass before delivery. ⋯ Women who are Jehovah's Witnesses are at a 44-fold increased risk of maternal death, which is due to obstetric hemorrhage. Patients should be counseled about this risk of death, and obstetric hemorrhage should be aggressively treated, including a rapid decision to proceed to hysterectomy when indicated.
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Am. J. Obstet. Gynecol. · Oct 2001
Randomized Controlled Trial Comparative Study Clinical TrialA randomized controlled trial comparing oxytocin administration before and after placental delivery in the prevention of postpartum hemorrhage.
To determine if the timing of the administration of prophylactic oxytocin influences the incidence of postpartum hemorrhage caused by uterine atony, retained placenta, and third-stage duration. ⋯ The administration of prophylactic oxytocin before placental delivery does not reduce the incidence of postpartum hemorrhage or third-stage duration, when compared with giving oxytocin after placental delivery. Early administration, however, does not increase the incidence of retained placenta.
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Am. J. Obstet. Gynecol. · Oct 2001
Comparative StudyThe effect of sequential use of vacuum and forceps for assisted vaginal delivery on neonatal and maternal outcomes.
To determine the risk of neonatal and maternal disease associated with the sequential use of vacuum and forceps compared with spontaneous vaginal delivery. ⋯ Sequential use of vacuum and forceps is associated with increased risk of both neonatal and maternal injury.