Neuroimaging clinics of North America
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Multiple sclerosis (MS) is the most common inflammatory demyelinating disorder of the central nervous system (CNS). MS has been subject to high-field magnetic resonance (MR) imaging research to a great extent during the past years, and much data has been collected that might be helpful in the investigation of other inflammatory CNS disorders. This article reviews the value of high-field MR imaging in examining inflammatory MS abnormalities. Furthermore, possibilities and challenges for the future of high-field MR imaging in MS are discussed.
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Neuroimaging Clin. N. Am. · May 2012
ReviewVascular disorders--magnetic resonance angiography: brain vessels.
Magnetic resonance angiography (MRA) of the brain obtained at 3 T imaging has made a significant clinical impact. MRA benefits from acquisition at higher magnetic field strength because of higher available signal-to-noise ratio and improved relative background suppression due to magnetic field strength-related T1 lengthening. Parallel imaging techniques are ideally suited for high-field MRA. Many of the developments that have made 3 T MRA of the brain successful can be regarded as enabling technologies that are essential for further development of 7 T MRA, which brings additional challenges.
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Neuroimaging Clin. N. Am. · May 2012
ReviewUltrahigh-field magnetic resonance imaging: the clinical potential for anatomy, pathogenesis, diagnosis and treatment planning in neck and spine disease.
An increase of the magnetic field strength to ultrahigh-field yields advantageous as well as disadvantageous changes in physical effects. The beneficial increase in signal/noise ratio can be leveraged into higher spatiotemporal resolution, and an exacerbation of artifacts can impede ultrahigh-field imaging. With the successful introduction of intracranial and musculoskeletal imaging at 7 T, recent advances in coil design have created opportunities for further applications of ultrahigh-field magnetic resonance (MR) imaging in other parts of the body. Initial studies in 7 T neck and spine MR imaging have revealed promising insights and new challenges, demanding further research and methodological optimization.
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Magnetic resonance (MR) imaging at 3 T has proved superior to 1.5 T in the brain for detecting numerous pathologic entities including hemosiderin, tiny metastases, subtle demyelinating plaques, active demyelinating plaques, and some epileptogenic foci, as well as small aneurysms with MR angiography. 3 T is superior to most advanced imaging techniques including diffusion, diffusion tensor imaging, perfusion, spectroscopy and functional MR imaging. The increased signal/noise ratio at 3 T permits higher spatial resolution. Initially spine imaging at 3 T proved more difficult with less successful results. During the past 7 years, technological advances in magnet and surface coil design as well as improved radio frequency transmitters and pulse sequence design in combination with the large body of knowledge accrued by radiologists and physicists during a nine year experience with clinical imaging of the spine with the doubled B0, has resulted in 3 T MRI of the spine achieving a reputation similar to that for brain imaging.
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Neuroimaging Clin. N. Am. · May 2012
ReviewDiffusion tensor and perfusion imaging of brain tumors in high-field MR imaging.
Diffusion tensor imaging (DTI) and perfusion-weighted imaging (PWI) are essential tools for diagnosing, differentiating, and monitoring brain tumors. High-field MRI provides higher signal-to-noise ratio, shorter scan time, and better image quality. ⋯ PWI provides reliable biomarkers for glioma grading, therapeutic responses, and differential diagnosis of various brain tumors. With higher field strength, better-quality DTI and PWI can raise the diagnostic accuracy in brain tumors.