Neuroimaging clinics of North America
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Neuroimaging Clin. N. Am. · Aug 2020
ReviewPET Imaging of Tumor Hypoxia in Head and Neck Cancer: A Primer for Neuroradiologists.
Tumor hypoxia is a known independent prognostic factor for adverse patient outcomes in those with head and neck cancer. Areas of tumor hypoxia have been found to be more radiation resistant than areas of tumor with normal oxygenation levels. ⋯ PET imaging is the gold standard method for imaging tumor hypoxia, with 18F-fluoromisonidazole the most extensively studied hypoxic imaging tracer. Newer tracers also show promise.
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Schizophrenia (Sz) is a chronic mental disorder characterized by disturbances in thought (such as delusions and confused thinking), perception (hearing voices), and behavior (lack of motivation). The lifetime prevalence of Sz is between 0.3% and 0.7%, with late adolescence and early adulthood, the peak period for the onset of psychotic symptoms. Causal factors in Sz include environmental and genetic factors and especially their interaction. About 50% of individuals with a diagnosis of Sz have lifelong impairment.
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Neuroimaging Clin. N. Am. · May 2020
ReviewMagnetoencephalography Research in Pediatric Autism Spectrum Disorder.
Magnetoencephalography (MEG) research indicates differences in neural brain measures in children with autism spectrum disorder (ASD) compared to typically developing (TD) children. As reviewed here, resting-state MEG exams are of interest as well as MEG paradigms that assess neural function across domains (e.g., auditory, resting state). To date, MEG research has primarily focused on group-level differences. Research is needed to explore whether MEG measures can predict, at the individual level, ASD diagnosis, prognosis (future severity), and response to therapy.
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This article provides an overview of research that uses magnetoencephalography to understand the brain basis of human language. The cognitive processes and brain networks that have been implicated in written and spoken language comprehension and production are discussed in relation to different methodologies: we review event-related brain responses, research on the coupling of neural oscillations to speech, oscillatory coupling between brain regions (eg, auditory-motor coupling), and neural decoding approaches in naturalistic language comprehension.