American journal of critical care : an official publication, American Association of Critical-Care Nurses
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Comparative Study
Adverse drug events in intensive care units: a cross-sectional study of prevalence and risk factors.
Adverse drug events are considered determinants of patient safety and quality of care. ⋯ Adverse drug events were common in intensive care unit patients and were associated with illness severity and nursing workload.
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Locked-in syndrome is an extremely rare neurological state caused by injury of the ventral pons. The syndrome is characterized by quadriplegia and anarthria with concomitant preservation of cortical function. ⋯ Because patients retain consciousness throughout their illness, a dependable method for titrating sedation may improve their quality of life. The case presented suggests that bispectral index monitoring may be a cost-effective and reliable method for managing sedation in patients with locked-in syndrome.