American journal of critical care : an official publication, American Association of Critical-Care Nurses
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Meta Analysis
Meta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework.
Between 30% and 80% of survivors of critical illness experience cognitive impairment, but the underlying mechanisms remain unknown. ⋯ Inflammatory biomarkers and amyloid β are associated with ICU delirium and point to potential overlapping mechanisms between delirium and ADRD. Critical care providers should consider integrating diagnostic approaches used in ADRD in their assessment of post-ICU cognitive dysfunction.