Surgical oncology clinics of North America
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Adjuvant therapy is commonly used in melanoma because recurrence after surgery usually results in the patient's eventual death. Surgeons have a profound influence on patients' decisions regarding adjuvant therapy, beginning with providing a clear understanding of the risk of specific types of recurrence. This review summarizes the potential oncologic benefits and relevant toxicities of adjuvant systemic therapies for melanoma that are currently available and under investigation.