The American journal of the medical sciences
-
Randomized Controlled Trial Comparative Study Clinical Trial
Comparative efficacy and potency of long-term therapy with glipizide or glyburide in patients with type 2 diabetes mellitus.
Long-term studies on the comparative efficacy and relative potency of glipizide and glyburide are sparse and controversial. ⋯ Glipizide and glyburide are effective in controlling hyperglycemia with similar doses in DM2. Glipizide exhibits greater reduction in FPG and 2PPG at 6 months. Additional studies are needed to validate equipotency of these drugs.