Transfusion medicine
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Transfusion medicine · Oct 2012
Multicenter StudyCryoprecipitate for transfusion: which patients receive it and why? A study of patterns of use across three regions in England.
Despite increasing interest in the use of fibrinogen concentrates, cryoprecipitate remains the major source of fibrinogen in England. ⋯ Wide variation in practice and dose suggests inconsistent practice and uncertainty in the evidence informing optimal use of cryoprecipitate.
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Transfusion medicine · Oct 2012
Multicenter Study Clinical TrialNational audit of the use of fibrinogen concentrate to correct hypofibrinogenaemia.
Massive haemorrhage occurs in a variety of clinical settings resulting in consumptive and dilutional coagulopathies leading to hypofibrinogenaemia. ⋯ Fibrinogen concentrate can be used to correct hypofibrinogenaemia and may reduce blood product usage.