European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
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Review Meta Analysis
Intrawound vancomycin to prevent infections after spine surgery: a systematic review and meta-analysis.
Post-operative spine surgical site infections are associated with substantial morbidity, mortality, and economic burden. Intrawound vancomycin may prevent infections after spine surgery, but recent studies have reported conflicting results. The objectives of this systematic review and meta-analysis were to determine: (1) In patients undergoing spine surgery, does the application of intrawound vancomycin lead to reduced rates of post-operative surgical site infections? (2) Are there differences in the estimates of effect between observational studies and randomized trials? (3) What adverse events are reported in the literature? ⋯ There is a lack of high-quality evidence to inform the use of intrawound vancomycin in spine surgery. Surgeons should be cautious before widely adopting this intervention and should be vigilant in monitoring for adverse effects. Further investigation with additional randomized controlled trials is justified.
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Randomized Controlled Trial Comparative Study
The prognostic value of electrodiagnostic testing in patients with sciatica receiving physical therapy.
To investigate the prognostic value of electrodiagnostic testing in patients with sciatica receiving physical therapy. ⋯ The presence of lumbosacral radiculopathy identified with electrodiagnostic testing is a favorable prognostic factor for recovery in low back pain-related disability regardless of physical therapy treatment received.
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Review Comparative Study
Cervical spondylodiscitis: change in clinical picture and operative management during the last two decades. A series of 50 patients and review of literature.
The incidence of spondylodiscitis is increasing. This study evaluates the behavior of cervical spondylodiscitis over a period of two decades in a single institution and compares the findings with the literature. ⋯ Cervical spondylodiscitis has increased and became more aggressive. While radical surgical debridement, stable reconstruction together with antibiotic therapy remained a reliable approach to achieve complete healing of the inflammation, anterior alone surgery became more applicable.
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Multicenter Study Observational Study
Surgical-site infection in spinal injury: incidence and risk factors in a prospective cohort of 518 patients.
To investigate the incidence of surgical-site infection (SSI) and determinate the risk factors of SSI in the context of spinal injury. ⋯ In this large prospective multicentre study in the context of spinal injury, we obtained an equivalent incidence rate and risk factors of SSI as found in the literature for elective spinal surgery.