Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
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Wall shear stress (WSS) appears to contribute significantly in the initiation and progression of atherosclerotic disease. The purpose of this work is to present in vivo systolic and diastolic WSS calculations in the human ascending aorta by the application of three straightforward methodologies based on Poiseuille's theory of flow. ⋯ In vivo calculation of WSS in the ascending aorta is feasible by phase-contrast MRI flow measurements and straightforward methodologies based on Poiseuille's theory of flow. However, measurements based on maximum flow velocity show larger deviations compared to measurements based on mean flow volume or mean flow velocity.