Addiction
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Randomized Controlled Trial Multicenter Study Comparative Study
Treatment retention among patients randomized to buprenorphine/naloxone compared to methadone in a multi-site trial.
To examine patient and medication characteristics associated with retention and continued illicit opioid use in methadone (MET) versus buprenorphine/naloxone (BUP) treatment for opioid dependence. ⋯ Provision of methadone appears to be associated with better retention in treatment for opioid dependence than buprenorphine, as does use of provision of higher doses of both medications. Provision of buprenorphine is associated with lower continued use of illicit opioids.