Addiction
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Randomized Controlled Trial Multicenter Study Comparative Study
Long-term outcomes after randomization to buprenorphine/naloxone versus methadone in a multi-site trial.
To compare long-term outcomes among participants randomized to buprenorphine or methadone. ⋯ There are few differences in long-term outcomes between buprenorphine and methadone treatment for opioid dependence, and treatment with each medication is associated with a strong reduction in opioid use.