Osteoarthritis and cartilage

The most recent articles from: Osteoarthr. Cartil. November 2019

Osteoarthr. Cartil. · Nov 2019

Randomized Controlled Trial Multicenter Study

Tropomyosin-related kinase A (TrkA) inhibition for the treatment of painful knee osteoarthritis: results from a randomized controlled phase 2a trial.

To investigate the TrkA inhibitor, ASP7962, for treatment of painful knee osteoarthritis. ⋯ Four-week treatment with ASP7962 (100 mg BID) did not improve pain or physical function in individuals with painful knee osteoarthritis. ClinicalTrials.gov, NCT02611466; EudraCT Number, 2014-004996-22.

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Osteoarthr. Cartil. · Nov 2019

Multicenter Study Observational Study

Clinical, humanistic, and economic burden of osteoarthritis among noninstitutionalized adults in the United States.

To estimate the burden of osteoarthritis (OA) among noninstitutionalized adults (≥18 years of age) in the US. ⋯ OA affects approximately 10% of noninstitutionalized adults in the US, resulting in substantial clinical, humanistic, and economic burdens.

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