Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Mar 2014
Sensitivity and associations with pain and body weight of an MRI definition of knee osteoarthritis compared with radiographic Kellgren and Lawrence criteria: a population-based study in middle-aged females.
Is a magnetic resonance imaging (MRI) definition for tibiofemoral osteoarthritis [(TFOAMRI) (definite osteophyte and full-thickness cartilage loss (or a combination of these factors with other MRI osteoarthritis (OA) features)] more sensitive to detect structural OA compared with the Kellgren & Lawrence (K&L) grading? And which definition shows the strongest association with (1) knee pain at baseline, (2) persistent knee pain during 2-year follow-up, (3) new onset of knee pain ±2 years later, and (4) body mass index (BMI). ⋯ TFOAMRI detects more cases of knee OA than K&L ≥ 2. Together with a better content validity and at least equal construct validity, we conclude that the TFOAMRI definition for knee OA is more sensitive in detecting structural knee OA.
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Osteoarthr. Cartil. · Mar 2014
Detection of cartilage damage in femoroacetabular impingement with standardized dGEMRIC at 3 T.
This study aimed at identifying the optimal threshold value to detect cartilage lesions with Standardized delayed Gadolinium-Enhanced MRI of Cartilage (dGEMRIC) at 3 T and evaluate intra- and inter-observer repeatability. ⋯ Standardized dGEMRIC at 3 T is accurate in detecting cartilage damage and could improve preoperative assessment in femoroacetabular impingement (FAI). As cartilage lesions in FAI are localized, visual inspection of the Standardized dGEMRIC maps is more accurate than an average z for the acetabular cartilage.
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Osteoarthr. Cartil. · Feb 2014
Comparative StudyComparative responsiveness of outcome measures for total knee arthroplasty.
The aim of this study was to compare the responsiveness of various patient-reported outcome measures (PROMs) and clinician-reported outcomes following total knee arthroplasty (TKA) over a 2-year period. ⋯ Outcome measures differ considerably in responsiveness, especially beyond one year post-operatively. Joint-specific outcome measures are more responsive than clinician-reported or generic health outcome tools. The FJS-12 was the most responsive of the tools assessed; suggesting that joint awareness may be a more discerning measure of patient outcome than traditional PROMs.
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Osteoarthr. Cartil. · Feb 2014
The relationship between knee pain characteristics and symptom state acceptability in people with knee osteoarthritis.
To examine the association between osteoarthritis (OA) pain characteristics and symptom acceptability. ⋯ In a community cohort with symptomatic knee OA, both the severity and predictability of intermittent knee pain contributed to symptom state acceptability. Unpredictable intermittent knee pain was more likely to be associated with an unacceptable symptom state than predictable intermittent pain. Research is warranted to elucidate potentially modifiable determinants of unpredictable intermittent pain in people with knee OA.
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Osteoarthr. Cartil. · Jan 2014
Longitudinal evaluation of T1ρ and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage.
To investigate longitudinal changes in laminar and spatial distribution of knee articular cartilage magnetic resonance imaging (MRI) T1ρ and T2 relaxation times, in individuals with and without medial compartment cartilage defects. ⋯ Spatial distribution of T1ρ and T2 relaxation time maps in medial knee OA using GLCM technique may be a sensitive indicator of cartilage deterioration, in addition to whole-compartment relaxation time data.