Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Sep 2013
Review Meta AnalysisAcupuncture and other physical treatments for the relief of pain due to osteoarthritis of the knee: network meta-analysis.
To compare the effectiveness of acupuncture with other relevant physical treatments for alleviating pain due to knee osteoarthritis. ⋯ As a summary of the current available research, the network meta-analysis results indicate that acupuncture can be considered as one of the more effective physical treatments for alleviating osteoarthritis knee pain in the short-term. However, much of the evidence in this area of research is of poor quality, meaning there is uncertainty about the efficacy of many physical treatments.
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Osteoarthr. Cartil. · Sep 2013
Review Meta AnalysisEfficacy of low frequency pulsed subsensory threshold electrical stimulation vs placebo on pain and physical function in people with knee osteoarthritis: systematic review with meta-analysis.
To determine if low frequency (≤100 Hz) pulsed subsensory threshold electrical stimulation produced either through pulsed electromagnetic field (PEMF) or pulsed electrical stimulation (PES) vs sham PEMF/PES intervention is effective in improving pain and physical function at treatment completion in adults with knee osteoarthritis (OA) blinded to treatment. ⋯ Current evidence of low and very low quality suggests that low frequency (≤100 Hz) pulsed subsensory threshold electrical stimulation produced either through PEMF/PES vs sham PEMF/PES is effective in improving physical function but not pain intensity at treatment completion in adults with knee OA blinded to treatment. Methodologically rigorous and adequately powered RCTs are needed to confirm the findings of this review.
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Osteoarthr. Cartil. · Sep 2013
Meta AnalysisStudies of pain management in osteoarthritis: bedside to policy.
Osteoarthritis (OA) is a debilitating chronic condition requiring long-term treatment of pain and functional impairment. Our objective was to characterize studies addressing management of OA-related pain with respect to the breadth of interventions, trial duration and size, outcome measures, and funding sources. ⋯ Over half of OA pain studies and >80% of those funded by industry used trial durations of less than 6 months. Future studies should take into consideration the need for long-term pain management for OA when designing trial protocols.
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Osteoarthr. Cartil. · Oct 2012
Review Meta AnalysisQuantitative sensory testing in painful osteoarthritis: a systematic review and meta-analysis.
To systematically review the use of quantitative sensory testing (QST) in pain characterisation (phenotyping) in osteoarthritis (OA). ⋯ QST of PPTs demonstrated good ability to differentiate between people with OA and healthy controls. Lower PPTs in people with OA in affected sites may suggest peripheral, and in remote sites central, sensitisation. PPT measurement merits further evaluation as a tool for phenotyping OA pain.
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Osteoarthr. Cartil. · Dec 2011
Review Meta AnalysisPre-operative interventions (non-surgical and non-pharmacological) for patients with hip or knee osteoarthritis awaiting joint replacement surgery--a systematic review and meta-analysis.
To determine if pre-operative interventions for hip and knee osteoarthritis provide benefit before and after joint replacement. ⋯ Low to moderate evidence from mostly small RCTs demonstrated that pre-operative interventions, particularly exercise, reduce pain for patients with hip and knee osteoarthritis prior to joint replacement, and exercise with education programs may improve activity after hip replacement.