Anaesthesia
-
A simple modification to an existing adult ventilator has been designed to permit mechanical ventilation of neonates and small children with the Ayre's T-piece circuit. The Nuffield Anaesthesia Ventilator Series 200 has been modified by replacing the piston in the patient valve with a fixed leak. ⋯ The modified ventilator is shown to perform as a time-cycled pressure generator capable of delivering tidal volumes between 10 and 300 ml at frequencies from 10 to 85/minute. It is therefore ideally suited to neonatal and paediatric use.
-
Randomized Controlled Trial Comparative Study Clinical Trial
ICI 35868 (Diprivan): a new intravenous anaesthetic. A comparison with Althesin.
ICI 35868 (Diprivan), 1-2 mg/kg was used to induce anaesthesia in 20 patients, and the results compared with induction of anaesthesia by Althesin 0.5 ml/kg given to a similar group of 20 patients. ICI 35868 was effective in inducing anaesthesia, but produced more respiratory depression, and cardiovascular effects which were significantly different from those produced by Althesin. ICI 35868 gave a smoother induction. It is concluded that ICI 35868 is a promising new induction agent which may also find application for the maintenance of anaesthesia.
-
Randomized Controlled Trial Comparative Study Clinical Trial
ICI 35868 (Diprivan): a new intravenous induction agent. A comparison with methohexitone.
ICI 35868 (Diprivan) has been used as an induction agent in patients undergoing minor gynaecological surgery and as the sole anaesthetic agent during bronchoscopy, and its effects were compared with those of methohexitone. The new agent proved to be satisfactory, although induction of anaesthesia was significantly longer than following methohexitone. complications were similar with both drugs. ICI 35868 deserves full investigation as an intravenous anaesthetic agent.