Anaesthesia
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A simple modification to an existing adult ventilator has been designed to permit mechanical ventilation of neonates and small children with the Ayre's T-piece circuit. The Nuffield Anaesthesia Ventilator Series 200 has been modified by replacing the piston in the patient valve with a fixed leak. ⋯ The modified ventilator is shown to perform as a time-cycled pressure generator capable of delivering tidal volumes between 10 and 300 ml at frequencies from 10 to 85/minute. It is therefore ideally suited to neonatal and paediatric use.
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Case histories of three patients with intractable pain, all of whom responded to epidural morphine, are presented. Drug tolerance appeared to develop in two patients who survived longer than 10 days. Nevertheless this method of pain relief may be a useful adjunct to terminal care and in certain circumstances may allow for easier management in the patient's own home.
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Randomized Controlled Trial Comparative Study Clinical Trial
Maternal opinion about analgesia for labour. A controlled trial between epidural block and intramuscular pethidine combined with inhalation.
In a randomised controlled trial epidural analgesia with bupivacaine 0.5% (mean dose 112.8 mg) was compared with pethidine (mean dose 200 mg) and inhalational analgesia in primipara (28 and 30 mothers) and multipara (17 and 18 mothers). Mothers who had an uneventful pregnancy and labour and agreed to have either treatment were studied during labour and followed-up at interviews for 5 months after delivery. Epidural block was rated significantly superior in respect of pain relief and comfort, there were no differences between the groups in reports of perineal discomfort. ⋯ Very few mothers, in each group, reported something missing in their experience of childbirth. Two thirds of each group would use the same method again. Epidural block can therefore be recommended to uncommitted mothers as a satisfying and effective method of pain relief for labour.