Der Anaesthesist
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Randomized Controlled Trial Clinical Trial
[Ropivacaine for spinal anesthesia. A dose-finding study].
Several clinical studies have demonstrated the efficacy of ropivacaine in different regional anaesthesia techniques, e.g., epidural anaesthesia. However, the efficacy of ropivacaine for spinal anaesthesia has only been demonstrated in animal experiments up to now. The objective of this study was the investigation of the efficacy and appropriate dosage of isobaric ropivacaine for spinal anaesthesia in humans. ⋯ At concentrations of 0.5% and 0.75%, ropivacaine results in long-lasting spinal anaesthesia. (A
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Randomized Controlled Trial Clinical Trial Controlled Clinical Trial
[Age-related correlation between EEG parameters and depth of anesthesia under propofol. Effect of fentanyl].
This study was designed to determine the relationship between the electroencephalogram (EEG) and clinical signs of depth of anaesthesia during induction of anaesthesia by slow infusion of propofol (18 mg/kg.h). ⋯ Different clinical signs corresponding to different levels of depth of anaesthesia could be differentiated by their EEG parameters. The EEG stage allowed better differentiation of the clinical conditions than the single-parameter EEG derivatives median and SEF. The results of this study show that EEG monitoring provides information about depth of anaesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
[Cost aspects in anesthesia. Propofol versus isoflurane anesthesia].
Cost control is no longer an option, but a necessity. Propofol anaesthesia is expensive, however, the true differences in comparison to volatile anaesthetics (isoflurane) are not known. ⋯ A climate of cost-consciousness and cost-containment prevails at the present time. The costs of propofol and 'standard' isoflurane anaesthesia were without differences; however, isoflurane used in a low-flow system had the lowest cost in this study. Doubts are justified, however, as to whether the choice of anaesthetic agents may considerably lower the costs of an anaesthesia department.