Der Anaesthesist
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Randomized Controlled Trial
[Influence of gender on the intubation conditions with rocuronium].
There is increasing evidence for gender differences in the pharmacokinetics and pharmacodynamics of anaesthetic drugs and neuromuscular blocking agents, e.g. rocuronium (Roc). Females require 30% less Roc than males to achieve the same degree of neuromuscular block and onset times are shorter. However, whether this leads to an improvement of the intubation conditions in females is unclear. ⋯ The intubation conditions after Roc were significantly better in women than in men. The differences were Roc-related and did not occur in the control groups.