American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Mar 2015
Novel Genes for Airway Wall Thickness Identified with Combined Genome Wide Association and Expression Analyses.
Airway wall thickness (AWT) is affected by both environmental and genetic factors and is strongly associated with airflow limitation in smaller airways. ⋯ Genetic variants contribute to AWT. Among others, the identified genes are also involved in emphysema, airway obstruction, and bronchial inflammation.