American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jul 2015
Letter Case Reports Randomized Controlled TrialLow-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension.
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Am. J. Respir. Crit. Care Med. · Jul 2015
Practice GuidelineAn Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline.
This document updates the American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on idiopathic pulmonary fibrosis treatment. ⋯ The panel formulated and provided the rationale for recommendations in favor of or against treatment interventions for idiopathic pulmonary fibrosis.
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Am. J. Respir. Crit. Care Med. · Jul 2015
The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis.
Chronic bronchitis (CB) is characterized by persistent cough and sputum production. Studies were performed to test whether mucus hyperconcentration and increased partial osmotic pressure, in part caused by abnormal purine nucleotide regulation of ion transport, contribute to the pathogenesis of CB. ⋯ Abnormal regulation of airway surface hydration may slow MCC in CB and contribute to disease pathogenesis.