American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Aug 2015
Randomized Controlled Trial Multicenter Study Comparative StudyUltrathin Bronchoscopy with Multimodal Devices for Peripheral Pulmonary Lesions: A Randomized Trial.
The combination of an ultrathin bronchoscope, navigational technology, and endobronchial ultrasound (EBUS) seems to combine the best of mutual abilities for evaluating peripheral pulmonary lesions, but ultrathin bronchoscopes that allow the use of EBUS have not been developed so far. ⋯ The diagnostic yield of the UTB method is higher than that of the TB-GS method. Clinical trial registered with www.umin.ac.jp/ctr/ (UMIN 000003177).
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Am. J. Respir. Crit. Care Med. · Aug 2015
Randomized Controlled TrialLVRS Improves Endothelial Function and Blood Pressure in Patients with COPD: A Randomized-controlled Trial.
Cardiovascular disease is a major cause of morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). Preliminary studies have shown that both airflow obstruction and systemic inflammation may contribute to endothelial dysfunction in COPD. Lung volume reduction surgery (LVRS) is a treatment option in selected patients with COPD with emphysema that improves breathing mechanics and lung function. ⋯ Endothelial function and blood pressure are improved 3 months after LVRS in patients with severe COPD and emphysema. LVRS may therefore have beneficial effects on cardiovascular outcomes. Clinical trial registered with www.clinicaltrials.gov (NCT 01020344).