American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Oct 2017
ReviewFifty Years of Research in ARDS. Respiratory Mechanics in Acute Respiratory Distress Syndrome.
Acute respiratory distress syndrome is a multifactorial lung injury that continues to be associated with high levels of morbidity and mortality. Mechanical ventilation, although lifesaving, is associated with new iatrogenic injury. ⋯ This review outlines the measurement and application of clinically applicable pulmonary mechanical concepts, such as plateau pressures, driving pressure, transpulmonary pressures, stress index, and measurement of strain. In addition, the concept of the "baby lung" and the utility of dynamic in addition to static measures of pulmonary mechanical variables are discussed.