American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jul 2017
Anti-histone Properties of C1 Esterase Inhibitor Protect Against Lung Injury.
Acute respiratory distress syndrome is characterized by alveolar epithelial cell injury, edema formation, and intraalveolar contact phase activation. ⋯ Collectively, C1INH administration provides a new therapeutic option for disorders associated with histone release.