Croatian medical journal
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Croatian medical journal · Jun 2022
The construction of the Split Sleep Questionnaire on sleep habits during the COVID-19 pandemic in the general population.
To construct a single-format questionnaire on sleep habits and mood before and during the COVID-19 pandemic in the general population. ⋯ The SSQ provides a valid, reliable, and efficient screening tool for the assessment of sleep habits and associated factors in the general population during the COVID-19 pandemic.
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To analyze an additional set of ˝Y-chromosome genetic markers to acquire a more detailed insight into the diversity of the Croatian population. ⋯ We obtained a new insight into the differences between examined subpopulations of Croatia and their possible (dis)similarities with neighboring and distant populations.
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Croatian medical journal · Jun 2022
Meta AnalysisGenetic sub-structuring of Croatian island populations in the Southeastern European context: a meta-analysis.
To use the method of meta-analysis to assess the influence of island population isolation on the sub-structuring of the Croatian population, as well as the influence of regional population groups on the sub-structuring of the Southeastern European population with regard to basic population genetic statistical parameters calculated by using STR locus analysis. ⋯ The higher structure of Croatian subpopulations in relation to Southeastern Europe suggest a certain degree of genetic isolation, most likely due to the influence of endogamy within rural island populations.
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Croatian medical journal · Jun 2022
The role of direct oral anticoagulants in the era of COVID-19: are antiviral therapy and pharmacogenetics limiting factors?
In patients with COVID-19, thromboinflammation is one of the main causes of morbidity and mortality, which makes anticoagulation an integral part of treatment. However, pharmacodynamic and pharmacokinetic properties of direct oral anticoagulants (DOACs) limit the use of this class of anticoagulants in COVID-19 patients due to a significant interference with antiviral agents. ⋯ Nevertheless, outpatients with a confirmed diagnosis of COVID-19 are recommended to continue prior DOAC therapy. More studies are required to clarify the pathogenesis of COVID-19-induced derangement of the coagulation system in order to recommend an appropriate anticoagulant treatment.
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Croatian medical journal · Jun 2022
Modeling the COVID-19 epidemic in Croatia: a comparison of three analytic approaches.
To facilitate the development of a COVID-19 predictive model in Croatia by analyzing three different methodological approaches. ⋯ Predicting future epidemic events remains difficult because modeling relies on the accuracy of the information on population structure and micro-environmental exposures, constant changes of the input parameters, varying societal adherence to anti-epidemic measures, and changes in the biological interactions of the virus and hosts.