Croatian medical journal
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Croatian medical journal · Aug 2022
More slices, less truth: effects of different test-set design strategies for magnetic resonance image classification.
To assess the effects of different test-set design strategies for magnetic resonance (MR) image classification using deep learning. ⋯ When deep learning is applied to MR image classification, training and test sets should consist of MR images of different patients. Models built on training and test sets consisting of images of the same patients yield optimistic error rates and lead to wrong conclusions. MR images of neighboring slices are so similar that they cause data leakage effect.
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Croatian medical journal · Aug 2022
ReviewTreatment of relapsing multiple sclerosis - recommendations of the Croatian Neurological Society.
Untreated multiple sclerosis (MS) irretrievably leads to severe neurological impairment. In European health care systems, patient access to disease modifying therapies (DMT) is often confined to more advanced stages of the disease because of restrictions in reimbursement. A discrepancy in access to DMTs is evident between West and East European countries. ⋯ If pwMS experience ≥1 relapse or ≥3 new T2 lesions while on platform therapies, they should be switched to high-efficacy DMT. Further efforts should be made to enable early and unrestricted access to high-efficacy DMT with a freedom of choice of an appropriate therapy for expert physicians and pwMS. The improvement of access to DMT achieved by the implementation of national treatment guidelines in Croatia can serve as an example to national neurological societies from other Eastern European countries to persuade payers to enable early and unrestricted treatment of pwMS.
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Croatian medical journal · Aug 2022
Liver transplantation in hepatocellular carcinoma - should we perform downstaging?
To compare the long-term outcomes between liver transplant (LT) recipients with hepatocellular carcinoma (HCC) who were downstaged with transarterial-chemoembolization (TACE) to the Milan criteria (MC) and those initially meeting the MC. ⋯ Patients successfully downstaged with TACE to the MC can achieve post-LT recipient and HCC recurrence-free survival comparable with patients initially within the MC. Good response to TACE as a criterion for LT may be a method of selecting patients with favorable biological characteristics.
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Croatian medical journal · Aug 2022
The COVID-19 lockdown promotes changes in sleep habits in the Croatian general population.
To investigate the effects of the coronavirus disease 2019 (COVID-19) lockdown on sleep habits in the Croatian general population. ⋯ The effect of the lockdown on sleep needs to be better understood. Sleep hygiene education could serve a first-line lifestyle intervention for people in lockdown experiencing sleep disruption.