Australian dental journal
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Australian dental journal · Sep 2015
Randomized Controlled Trial Comparative StudyEffects of curcumin on crevicular levels of IL-1β and CCL28 in experimental gingivitis.
Curcumin has anti-inflammatory properties. The aim of this study was to compare interleukin-1β (IL-1β) and chemokine (C-C motif) ligand 28 (CCL28) levels following a topical application of curcumin (CRM), chlorhexidine (CHX) and chlorhexidine-metronidazole (CHX-MTZ) in an experimental gingivitis human model. ⋯ The anti-inflammatory potential of topical curcumin was similar to CHX-MTZ but superior to CHX in affecting IL-1β and CCL28 levels.
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Australian dental journal · Sep 2011
Randomized Controlled Trial Comparative StudyInhaled methoxyflurane (Penthrox) sedation for third molar extraction: a comparison to nitrous oxide sedation.
The aim of this study was to evaluate the use of inhaled methoxyflurane (Penthrox) in the reduction of dental anxiety in patients undergoing mandibular third molar removal in a specialist surgical suite and compare it to the conventional nitrous oxide sedation. ⋯ The Penthrox Inhaler can produce a comparable sedation to that of nitrous oxide for the surgical extraction of third molars under local anaesthesia.
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Australian dental journal · Dec 2009
Randomized Controlled TrialPre-emptive ibuprofen arginate in third molar surgery: a double-blind randomized controlled crossover clinical trial.
This study evaluated the effectiveness of 400 mg ibuprofen arginate either as a pre-emptive (PRE group) or postoperative (POST group) analgesic using a common dental pain model. ⋯ Ibuprofen arginate may be considered effective in reducing surgically induced moderate to severe pain when administered either pre-operatively or postoperatively due to the reported relatively low pain score, less consumption of rescue medication, delayed onset of pain, good number of pain-free patients and a high rating in the global assessment score.
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Australian dental journal · Dec 2006
Randomized Controlled TrialEfficacy of pilocarpine lozenge for post-radiation xerostomia in patients with head and neck cancer.
Patients with radiation-induced xerostomia produce little or no saliva. Several studies have demonstrated the efficacy of systemic administration of pilocarpine hydrochloride in individuals with post-radiation xerostomia. However, analysis of pilocarpine lozenges for treatment of post-radiation xerostomia in patients with head and neck cancer has not been reported. ⋯ The 5-mg pilocarpine lozenge produced the best clinical results, but further investigation with a larger group of patients is required.
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Australian dental journal · Dec 2002
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialA study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia.
The aim of this study was to evaluate the comparative efficacy of three commonly used analgesics (Panadeine, Diflunisal and Etodolac) in the control of pain after third molar surgery under local anaesthesia. ⋯ Diflunisal is superior in the control of pain following third molar surgery under local anaesthesia than either Panadeine or Etodolac, and has few side effects.