International journal of food sciences and nutrition
-
Int J Food Sci Nutr · Nov 2012
Randomized Controlled Trial Clinical TrialEffect of substituting saturated with monounsaturated fatty acids on serum visfatin levels and insulin resistance in overweight women: a randomized cross-over clinical trial.
This study aimed to determine the effects of a monounsaturated fatty acids (MUFA)-rich diet on serum visfatin, interleukin-6 and insulin levels among overweight women. ⋯ Our findings did not support any significant effect of a MUFA-rich intake on serum IL-6 and insulin levels as compared with a SFA-rich diet; however, it has the potential to favourably affect serum visfatin levels.
-
Int J Food Sci Nutr · Jan 2009
Randomized Controlled Trial Comparative Study Clinical TrialVitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy.
Despite many therapeutic options, painful diabetic neuropathy is still a common and challenging complication of diabetes mellitus and is often resistant to treatment with current modalities. ⋯ In conclusion, vitamin B(12) is more effective than nortriptyline for the treatment of symptomatic painful diabetic neuropathy.
-
Int J Food Sci Nutr · Aug 2007
Randomized Controlled TrialEffects of advice on dietary intake and/or physical activity on body composition, blood lipids and insulin resistance following a low-fat, sucrose-containing, high-carbohydrate, energy-restricted diet.
To determine the effect of dietary advice in conjunction with advice to increase physical activity on the body composition, blood lipid and insulin profiles in overweight women. ⋯ A low-fat, high-carbohydrate, sucrose-containing diet combined with increased physical exercise resulted in greater health benefits than diet or physical activity advice alone.
-
Int J Food Sci Nutr · Jun 2007
Randomized Controlled TrialModerate-carbohydrate low-fat versus low-carbohydrate high-fat meal replacements for weight loss.
To compare the efficacy of a low-carbohydrate high-fat versus a moderate-carbohydrate low-fat diet for weight loss and cardiovascular risk reduction. ⋯ Moderate approaches to weight loss such as a moderate-carbohydrate low-fat diet may be prudent.
-
Int J Food Sci Nutr · Nov 2006
Randomized Controlled TrialComparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10).
The relative bioavailability of coenzyme Q10 (CoQ10) is markedly influenced by its delivery systems. The aim of this study was to compare four standard CoQ10 supplements available on the market with a novel solubilizate formulation of CoQ10 (Solu Q10). Pharmacokinetic parameters were assessed in 54 healthy volunteers after single and multiple intakes of 60 mg CoQ10 over a time period of 14 days. ⋯ Long-term supplementation resulted in significantly higher plasma levels (P<0.01) for all formulations, with Solu Q10 performing best. Intracellular CoQ10 levels measured in buccal mucosa cells were increased (P<0.05) in response to supplementation when starting within the physiological range. In summary, solubilizates were clearly superior to oily dispersions and crystalline CoQ10 in their overall bioavailability, with the best absorption characteristics seen for the novel Solu Q10 solubilizate.