Canadian respiratory journal : journal of the Canadian Thoracic Society
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Randomized Controlled Trial Comparative Study
Prophylactic positive end-expiratory pressure and postintubation hemodynamics: an interventional, randomized study.
To investigate the hemodynamic and outcome effects of implementing prophylactic positive end-expiratory pressure (PEEP) versus zero end-expiratory pressure (ZEEP) in patients during the postintubation period in the emergency setting. ⋯ In the present trial, there was no evidence that implementing a prophylactic PEEP of 5 cmH2O adversely affects short-term hemodynamics or outcome in medical intensive care patients during the postintubation period.
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Review Case Reports
Rare lung diseases III: pulmonary Langerhans' cell histiocytosis.
Pulmonary Langerhans' cell histiocytosis (PLCH) is an unusual cystic lung disease that is also characterized by extrapulmonary manifestations. The current review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case. ⋯ A major theme of the current series of articles on rare lung diseases has been the translation of insights gained from fundamental research to the clinic. Accordingly, the understanding of dendritic cell biology in this disease has led to important advances in the care of patients with PLCH.
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Despite evidence supporting the role of noninvasive ventilation (NIV) in diverse populations, few publications describe how NIV is used in clinical practice. ⋯ The present study illustrates how NIV is used in clinical practice and confirms that NIV initiation has increased over time.