JNMA; journal of the Nepal Medical Association
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JNMA J Nepal Med Assoc · Jul 2020
ReviewBlood-based Biomarkers for Early Diagnosis of Lung Cancer: A Review Article.
Lung cancer is the severe leading cause of cancer-related mortality worldwide. Early detection of lung cancer can significantly increase their survival rate. ⋯ Similarly, lung tumor tissue as invasive and difficult to obtain and potentially risky procedures, there is the immediate need of non-invasive, novel sensitive and reliable blood-based tumor markers which now has become an important area on research. This review will mainly focus on recently identified circulating biomarkers: circulating tumor cells, circulating tumor deoxyribonucleic acid, tumor-derived exosomes, circulating ribonucleic acid and micro ribonucleic acid, and tumoreducated platelets which may enable earlier diagnosis of lung cancer and their application in clinical practices.
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JNMA J Nepal Med Assoc · Jul 2020
Quarantine: A Period of Self-discovery and Motivation as Medical Student.
The ongoing nationwide lockdown due to the global pandemic COVID-19 started from March 24, 2020, in Nepal. Lots of medical students are in dilemma about how to utilize this time to make it more productive. ⋯ This difficult time demands resilience. This article focuses on some ideas to discover ourselves and develop resilience within us.
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JNMA J Nepal Med Assoc · Jul 2020
Case ReportsMyocysticercosis as a Rare Cause of Hand Swelling involving Thenar Group of Muscles: A Case Report.
Larval form of Taenia solium causes cysticercosis that commonly involves the central nervous system. Other sites of manifestation are eye, gastrointestinal system, skeletal muscles and subcutaneous tissues. Isolated muscular involvement is rare with only a handful of cases reported in the literature. ⋯ This should be considered in differential diagnosis in our developing nation and especially in endemic region. High resolution ultrasound of the hand (thenar region) helped in the diagnosis and is often diagnostic like in our case. The treatment of choice of an isolated symptomatic lesion without involvement of central nervous system is surgical excision which we did followed by short course of antiheminthic and anti-inflammatory medication for two weeks.