JNMA; journal of the Nepal Medical Association
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JNMA J Nepal Med Assoc · Dec 2021
Total Knee Arthroplasty in Moderate to Severe Fixed Flexion Deformity in a Tertiary Care Center: A Descriptive Cross-sectional Study.
Performing the total knee arthroplasty in moderate to severe fixed flexion deformity, appropriate resection of bone from distal femur along with proper ligament balancing is mandatory in order to get the reasonable intraoperative correction. The aim of our study is to find out the prevalence of total knee arthroplasty among knees with moderate to severe fixed flexion deformity in a tertiary care center. ⋯ The prevalence of total knee arthroplasty is comparable to other study. In our study total knee arthroplasty can be performed successfully with excellent functional outcomes in patients with moderate to severe fixed flexion deformity of knee joint provided the joint stability is maintained by appropriate ligamentous balancing.
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JNMA J Nepal Med Assoc · Dec 2021
Case ReportsEpithelioid Gastrointestinal Stromal Tumor of Duodenum Mimicking Adenocarcinoma: A Case Report.
Gastrointestinal stromal tumor is a mesenchymal tumor of gastro-intestinal tract. This epithelioid type gastrointestinal stromal tumor seen in a 22-year-old male with epigastric pain as a presenting symptom had morphological resemblance to carcinoma. However, the immunohistochemistry profile with CD117 and DOG 1 positivity, combined with AE1/AE3 positivity confirmed the tumor as gastrointestinal stromal tumor. ⋯ The treatment approach of CD117 positivity in gastrointestinal stromal tumor has therapeutic benefit with tyrosine kinase inhibitors. Preoperative Imatinib therapy with complete excision can decrease the disease recurrence. Histopathological examination with immunohistochemical studies help to reach the definite diagnosis.
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JNMA J Nepal Med Assoc · Dec 2021
Hyponatremia in Chronic Liver Disease among Patients Presenting to a Tertiary Care Hospital: A Descriptive Cross-sectional Study.
Hyponatremia is a frequent problem in chronic liver disease. To the best of our knowledge, no study of hyponatremia in chronic liver disease has been conducted in our setting. The aim of this study is to study the prevalence of hyponatremia in patients with chronic liver disease attending the outpatient department of a tertiary care hospital. ⋯ The prevalence of hyponatremia among patients with chronic liver disease was found to be higher when compared to other similar studies.
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JNMA J Nepal Med Assoc · Dec 2021
Endoscopic Septoturbinoplasty among Patients Undergoing Surgery in the Department of Otolaryngology-Head and Neck of a Tertiary Care Hospital: A Descriptive Cross-sectional Study.
Septoplasty without turbinoplasty is one of the main reasons for failure of procedure in case of deviated nasal septum with inferior turbinate hypertrophy. Septoturbinoplasty is the procedure of choice for complete treatment. The main objective is to find out the prevalence of endoscopic septoturbinoplasty among patients undergoing surgery in Department of Otolaryngology-Head and Neck of a tertiary care hospital. ⋯ The prevalence of septoturbinoplasty in our study is similar to other studies done in similar settings. We found almost complete resolution of breathing problems following endoscopic septoturbinoplasty, hence improving quality of life.
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JNMA J Nepal Med Assoc · Dec 2021
Ulinastatin in the Management of Severe Acute Alcoholic Pancreatitis: A Case Series.
Severe acute alcoholic pancreatitis is a second common form of pancreatitis that requires intensive care unit care and has high morbidity and mortality due to lacking specific treatment. Management of alcoholic pancreatitis is generally non- specific and supportive. We hereby present a case-series of three patients that describes the successful treatment of severe acute alcoholic pancreatitis with ulinastatin and other supportive treatment. From this we want to emphasize that ulinastatin a protease inhibitor can be used in the treatment of alcoholic pancreatitis.