Academic radiology
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Review Meta Analysis
A systematic review and meta-analysis of the accuracy of diffusion-weighted MRI in the detection of malignant pulmonary nodules and masses.
To perform a meta-analysis to assess the diagnostic performance of the diffusion-weighted magnetic resonance imaging (DWI) technique in discrimination of benign and malignant pulmonary nodules or masses. ⋯ With respect to the accuracy and DOR, DWI is useful for differentiation between malignant and benign pulmonary nodules or masses. Diagnostic test accuracy is not the be-all and end-all of diagnostic testing. Concerning PLR and NLR, DWI may not help to alter posttest probability compared to pretest probability to sufficiently alter physician's decision making. Future analyses should be conducted in large-scale, high-quality trials to evaluate its clinical value and establish standards of DWI measurement, analysis, and cutoff values of diagnosis.
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To test the ability of quantitative measures from preoperative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to predict, independently and/or with the Katz pathologic nomogram, which breast cancer patients with a positive sentinel lymph node biopsy will have four or more positive axillary lymph nodes on completion axillary dissection. ⋯ Integration of DCE-MRI primary lesion kinetics significantly improved the Katz pathologic nomogram accuracy to predict the presence of metastases in four or more nodes. DCE-MRI may help identify sentinel node-positive patients requiring further local-regional therapy.
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Magnetic resonance (MR) perfusion techniques and MR spectroscopy (MRS) provide specific physiological information that may allow distinction between recurrent glioma and progression from stable disease. ⋯ MR perfusion techniques and MRS are useful tools that enable improved differentiation between recurrent glioma and stable disease. Among the single parameters, DSC showed the best diagnostic performance. Multiparametric assessment substantially improved the ability to differentiate the two entities.
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To investigate the relationship between apparent diffusion coefficient (ADC) values and the Ki-67 staining index (Ki-67 SI), a tumor proliferation marker, in prostate cancer (PCa). ⋯ The ADC values of PCa could reflect the tumor proliferative activity and the differentiated degree of PCa.
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To compare initial evaluations of chest dual-energy subtraction digital tomosynthesis (DES-DT) and dual-energy subtraction radiography (DES-R) for detection of pulmonary nodules. ⋯ Compared with DES-R, DES-DT provided greater sensitivity for detection of pulmonary nodules, particularly for the larger ones.