Academic radiology
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We aimed to assess the prevalence of significant computed tomographic(CT) manifestations and describe some notable features based on chest CT images, as well as the main clinical features of patients with coronavirus disease 2019(COVID-19). ⋯ Chest CT manifestations in patients with COVID-19, as well as its main clinical characteristics, might be helpful in disease evolution and management.
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Review Meta Analysis
A systematic review and meta-analysis of the accuracy of diffusion-weighted MRI in the detection of malignant pulmonary nodules and masses.
To perform a meta-analysis to assess the diagnostic performance of the diffusion-weighted magnetic resonance imaging (DWI) technique in discrimination of benign and malignant pulmonary nodules or masses. ⋯ With respect to the accuracy and DOR, DWI is useful for differentiation between malignant and benign pulmonary nodules or masses. Diagnostic test accuracy is not the be-all and end-all of diagnostic testing. Concerning PLR and NLR, DWI may not help to alter posttest probability compared to pretest probability to sufficiently alter physician's decision making. Future analyses should be conducted in large-scale, high-quality trials to evaluate its clinical value and establish standards of DWI measurement, analysis, and cutoff values of diagnosis.
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Review Meta Analysis Comparative Study
Meta-analysis: comparison of F-18 fluorodeoxyglucose-positron emission tomography and bone scintigraphy in the detection of bone metastasis in patients with lung cancer.
The aim of this review was to evaluate the diagnostic properties of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) or PET/computed tomography (CT) and bone scintigraphy in the detection of osseous metastases in patients with lung cancer. ⋯ Although FDG-PET or PET/CT has higher sensitivity and specificity than bone scintigraphy, further research with a less biased design is needed to determine the most efficacious imaging modality for the detection of metastatic lung cancer.
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To determine the accuracy of 64-section coronary computed tomography angiography (CCTA) in predicting 30 day major adverse cardiac events (MACE) for patients presenting with symptoms concerning for acute coronary syndrome (ACS). ⋯ Sixty-four section CCTA had a 99.3% negative predictive value in excluding MACE for 30 days after initial symptom presentation in 85.2% of our study population. Although the value of 64-section CCTA is best for identifying patients who can safely be discharged home, it is less useful for patients who have positive results.
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In summary, the radiology outcomes research literature is both extensive and broad. The methodologic quality, however, is quite variable. Overall, this quality could be improved by intervention in two areas: methodologic dissemination and development. ⋯ Traditionally, National Cancer Institute and other National Institutes of Health and public sector funding has been predicated on a high level of research sophistication. Undoubtedly, availability of grants for diagnostic and screening imaging clinical trials and other research will go far to improve radiology research methods. The other traditional source of research funding is industry.