Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
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Ann. Allergy Asthma Immunol. · Mar 2015
Randomized Controlled TrialEffectiveness of ecallantide in treating angiotensin-converting enzyme inhibitor-induced angioedema in the emergency department.
Angiotensin-converting enzyme inhibitor-induced angioedema (ACEI-AE) is mediated by bradykinin. There remains an unmet treatment need because these patients, when presenting to the emergency department (ED), do not respond to conventional therapies, such as antihistamines and corticosteroids. ⋯ The results from this preliminary study reveal that ecallantide is safe to use and may increase the proportion of patients who meet early discharge criteria by approximately10%. A larger phase 3 study is necessary to confirm the efficacy and evaluate the cost-effectiveness of ecallantide use for ACEI-AE in the ED setting.
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Ann. Allergy Asthma Immunol. · Dec 2014
Letter Randomized Controlled Trial Multicenter StudySublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized, open, parallel-group study.
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Ann. Allergy Asthma Immunol. · Oct 2014
Randomized Controlled Trial Comparative StudyPatient perceptions of asthma-related financial burden: public vs. private health insurance in the United States.
Given the complexity of the health insurance market in the United States and the confusion that often stems from these complexities, patient perception about the value of health insurance in managing chronic disease is important to understand. ⋯ African American women who perceive asthma as a financial burden regardless of health insurance report more urgent health care visits and lower quality of life. Burden may be present despite having and being able to generate economic resources and health insurance. Further policy efforts are indicated and special attention should focus on type of coverage.
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Ann. Allergy Asthma Immunol. · May 2014
Letter Randomized Controlled TrialInfluence of β2-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma.
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Ann. Allergy Asthma Immunol. · Dec 2012
Randomized Controlled TrialSensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma.
Impulse oscillometry (IOS) provides an alternative method of assessing pulmonary function to conventional spirometry. ⋯ IOS is a more sensitive response outcome than spirometry with respect to bronchoconstriction to oral propranolol and bronchodilatation after salbutamol in patients with mild to moderate asthma.