Journal of the International Neuropsychological Society : JINS
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J Int Neuropsychol Soc · Oct 2017
ReviewThe Many Sides of Hemispheric Asymmetry: A Selective Review and Outlook.
Hemispheric asymmetry is commonly viewed as a dual system, unique to humans, with the two sides of the human brain in complementary roles. To the contrary, modern research shows that cerebral and behavioral asymmetries are widespread in the animal kingdom, and that the concept of duality is an oversimplification. ⋯ Unlike the asymmetries of the internal organs, brain asymmetry is variable, with a significant minority of the population showing reversed asymmetries or the absence of asymmetry. This variability may underlie the divisions of labor and the specializations that sustain social life. (JINS, 2017, 23, 710-718).
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J Int Neuropsychol Soc · Nov 2010
ReviewMild traumatic brain injury and postconcussive symptoms in children and adolescents.
The vast majority of traumatic brain injuries (TBI) in children are of mild severity. Even if only a small proportion of children with mild TBI suffer negative outcomes, then mild TBI is a serious public health problem. This review summarizes the literature regarding the neurobehavioral outcomes associated with mild TBI in children and adolescents, focusing on the longstanding debate regarding postconcussive symptoms and attendant conceptual and methodological issues. The review also discusses future research directions, the long-term goal of which is to develop a comprehensive and integrated biopsychosocial model of outcomes that helps guide clinical management.
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J Int Neuropsychol Soc · May 2007
ReviewMeasurement of cerebral perfusion with arterial spin labeling: Part 1. Methods.
Arterial spin labeling (ASL) is a magnetic resonance imaging (MRI) method that provides a highly repeatable quantitative measure of cerebral blood flow (CBF). As compared to the more commonly used blood oxygenation level dependent (BOLD) contrast-based methods, ASL techniques measure a more biologically specific correlate of neural activity, with the potential for more accurate estimation of the location and magnitude of neural function. ⋯ ASL measures of perfusion can aid in the interpretation of the BOLD signal change and, when combined with BOLD, can measure the change in oxygen utilization accompanying changes in behavioral state. Whether used alone to probe neural activity or in combination with BOLD techniques, ASL methods are contributing to the field's understanding of healthy and disordered brain function.