Current opinion in critical care
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Curr Opin Crit Care · Aug 2022
Review Meta AnalysisUpdate on vitamin C administration in critical illness.
Several studies have recently explored the effects of intravenous vitamin C in sepsis. We aimed to summarize their findings to provide perspectives for future research. ⋯ The effect of intravenous vitamin C in critically ill patients has yet to be determined and might be dose-dependent. Clinical studies of very high or mega doses of vitamin C are justified by preclinical data.