Clinical drug investigation
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Randomized Controlled Trial
Saxagliptin add-on therapy to insulin with or without metformin for type 2 diabetes mellitus: 52-week safety and efficacy.
Achievement of glycemic control is an important objective in the management of type 2 diabetes mellitus (T2DM). ⋯ Saxagliptin 5 mg once daily as add-on to insulin, with or without concomitant metformin, produced a durable improvement in glycemic control and was well tolerated over 52 weeks of treatment.