Journal of pediatric hematology/oncology
-
J. Pediatr. Hematol. Oncol. · Dec 2001
Review Comparative StudyLow relapse rate in children with acute lymphoblastic leukemia after risk-directed therapy.
Even though acute lymphoblastic leukemia (ALL) responds well to chemotherapy, relapse remains the major problem. This study documents relapse and survival rates in 85 consecutive children (33 at good risk, 52 at high risk) with ALL diagnosed in 1991 to 1996. ⋯ The modification proved to be effective in diminishing the therapeutic toxicity and improving the efficacy, mainly for the high-risk group.