Journal of pediatric hematology/oncology
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J. Pediatr. Hematol. Oncol. · Jan 2003
Multicenter Study Clinical TrialRecombinant tissue plasminogen activator (alteplase) for restoration of function to occluded central venous catheters in pediatric patients.
To evaluate the safety and efficacy of alteplase for restoring function to occluded central venous catheters in a pediatric population. ⋯ An alteplase regimen of up to two 2-mg doses is safe and effective for restoration of function to occluded central venous catheters in a pediatric population.