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European journal of neurology : the official journal of the European Federation of Neurological Societies
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Randomized Controlled Trial
Modulatory effects of anodal transcranial direct current stimulation on perception and pain thresholds in healthy volunteers.
We aimed to evaluate whether transcranial direct current stimulation (tDCS) is effective in modulating sensory and pain perception thresholds in healthy subjects as to further explore mechanisms of tDCS in pain relief. ⋯ These results show that both M1 and DLFPC anodal tDCS can be used to modulate pain thresholds in healthy subjects; thus, the mechanism of tDCS in modulating pain involves pathways that are independent of abnormal pain-related neural activity.