Multiple sclerosis : clinical and laboratory research
-
Randomized Controlled Trial Clinical Trial
A randomized, double-blind, placebo-controlled pilot study of i.v. immune globulins in combination with i.v. methylprednisolone in the treatment of relapses in patients with MS.
Some patients with multiple sclerosis (MS) do not show a clear improvement of acute relapses after treatment with intravenous methylprednisolone (IVMP). We compared the efficacy of the combination of intravenous immunoglobulins (IVIg) and IVMP with the standard treatment of IVMP alone in promoting recovery from moderate to severe acute relapses in MS. ⋯ Our study could not show superiority of IVMP-IVIg in the treatment of moderate to severe acute relapses in MS.