Heart : official journal of the British Cardiac Society
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Randomized Controlled Trial Comparative Study
A randomised, controlled study of rate versus rhythm control in patients with chronic atrial fibrillation and heart failure: (CAFE-II Study).
Atrial fibrillation (AF) and heart failure (HF) often coexist. The aim was to investigate whether restoring sinus rhythm (SR) could improve cardiac function, symptoms, exercise capacity and quality of life (QoL) in patients with chronic heart failure. ⋯ Restoring SR in patients with AF and heart failure may improve QoL and LV function when compared with a strategy of rate control.
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Review Meta Analysis
Meta-analysis of randomised trials comparing the effectiveness of miniaturised versus conventional cardiopulmonary bypass in adult cardiac surgery.
The aim of this meta-analysis is to summarise the results of prospective, randomised studies comparing miniaturised (Mini-CPB) versus conventional cardiopulmonary bypass (C-CPB). ⋯ This meta-analysis suggests that the use of Mini-CPB may be associated with lower risk of postoperative stroke and blood losses and with a somewhat decreased mortality. However, due to the large heterogeneity of methods and the small number of studies and patients evaluated so far, larger and homogeneous studies should be performed to obtain more conclusive results on the safety and efficacy of Mini-CPB.