Heart : official journal of the British Cardiac Society
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Randomized Controlled Trial Multicenter Study
Limit of detection of troponin discharge strategy versus usual care: randomised controlled trial.
The clinical effectiveness of a 'rule-out' acute coronary syndrome (ACS) strategy for emergency department patients with chest pain, incorporating a single undetectable high-sensitivity cardiac troponin (hs-cTn) taken at presentation, together with a non-ischaemic ECG, remains unknown. ⋯ The LoDED strategy facilitates safe early discharge in >40% of patients with chest pain. Clinical effectiveness is variable when compared with existing rule-out strategies and influenced by wider system factors.