Annals of internal medicine
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Randomized Controlled Trial Multicenter Study Clinical Trial
Central venous catheters coated with minocycline and rifampin for the prevention of catheter-related colonization and bloodstream infections. A randomized, double-blind trial. The Texas Medical Center Catheter Study Group.
Central venous catheters are a principal source of nosocomial bloodstream infections, which are difficult to control. ⋯ Central venous catheters coated with minocycline and rifampin can significantly reduce the risk for catheter-related colonization and bloodstream infections. The use of these catheters may save costs.