Annals of internal medicine
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Randomized Controlled Trial Comparative Study Clinical Trial
Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis.
Preventive therapy is an important element of syphilis control efforts. No currently recommended, single-dose alternatives to penicillin G benzathine are available for treatment of incubating syphilis. ⋯ A single 1.0-g dose of azithromycin seems to be efficacious for prevention of syphilis in persons exposed to infected sexual partners.