Annals of internal medicine
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Review Meta Analysis
Systematic review: glucose control and cardiovascular disease in type 2 diabetes.
Results from clinical trials examining the effect of intensive glucose control on cardiovascular disease have been conflicting. ⋯ Intensive glucose control reduced the risk for some cardiovascular disease outcomes (such as nonfatal myocardial infarction), did not reduce the risk for cardiovascular death or all-cause mortality, and increased the risk for severe hypoglycemia.