Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Metoprolol versus amiodarone in the prevention of atrial fibrillation after cardiac surgery: a randomized trial.
Current guidelines recommend β-blockers as the first-line preventive treatment of atrial fibrillation (AF) after cardiac surgery. Despite this, 19% of physicians report using amiodarone as first-line prophylaxis of postoperative AF. Data directly comparing the efficacy of these agents in preventing postoperative AF are lacking. ⋯ The Finnish Foundation for Cardiovascular Research and the Kuopio University EVO Foundation.