Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Doxycycline for stabilization of abdominal aortic aneurysms: a randomized trial.
Doxycycline inhibits formation and progression of abdominal aortic aneurysms (AAAs) in preclinical models of the disease, but it is unclear whether and how this observation translates to humans. ⋯ The Netherlands Organisation for Health Research and Development, and the NutsOhra Fund.
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Practice Guideline
Screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease: A clinical practice guideline from the American College of Physicians.
The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the screening, monitoring, and treatment of adults with stage 1 to 3 chronic kidney disease. ⋯ ACP recommends that clinicians choose statin therapy to manage elevated low-density lipoprotein in patients with stage 1 to 3 chronic kidney disease. (Grade: strong recommendation, moderate-quality evidence).