Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Oral high-dose multivitamins and minerals after myocardial infarction: a randomized trial.
Whether high-dose multivitamins are effective for secondary prevention of atherosclerotic disease is unknown. ⋯ National Institutes of Health.
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Randomized Controlled Trial Multicenter Study
Doxycycline for stabilization of abdominal aortic aneurysms: a randomized trial.
Doxycycline inhibits formation and progression of abdominal aortic aneurysms (AAAs) in preclinical models of the disease, but it is unclear whether and how this observation translates to humans. ⋯ The Netherlands Organisation for Health Research and Development, and the NutsOhra Fund.
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Atrial fibrillation (AF) prediction models have unclear clinical utility given the absence of AF prevention therapies and the immutability of many risk factors. Premature atrial contractions (PACs) play a critical role in AF pathogenesis and may be modifiable. ⋯ American Heart Association, Joseph Drown Foundation, and National Institutes of Health.