Annals of internal medicine

The most recent articles from: Ann. Intern. Med. April 2020

Ann. Intern. Med. · Apr 2020

Randomized Controlled Trial Multicenter Study

Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial.

Iron chelation therapy (ICT) in patients with lower-risk myelodysplastic syndromes (MDS) has not been evaluated in randomized studies. ⋯ Novartis Pharma AG.

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Ann. Intern. Med. · Apr 2020

Randomized Controlled Trial Multicenter Study

Effects of Interleukin-1β Inhibition on Incident Anemia: Exploratory Analyses From a Randomized Trial.

Inflammatory cytokines, such as interleukin (IL)-1β, alter iron homeostasis and erythropoiesis, resulting in anemia, but whether inhibition of IL-1β can reverse these effects is unclear. ⋯ Novartis Pharmaceuticals.

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Ann. Intern. Med. · Apr 2020

Randomized Controlled Trial

Immunogenicity, Safety, and Efficacy of a Standalone Universal Influenza Vaccine, FLU-v, in Healthy Adults: A Randomized Clinical Trial.

FLU-v is a broad-spectrum influenza vaccine that induces antibodies and cell-mediated immunity. ⋯ SEEK and the European Commission Directorate-General for Research and Innovation, European Member States within the UNISEC (Universal Influenza Vaccines Secured) project.

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